I is 900000000 K is 1000000000
900000000 900499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 900500000 K is 1000000000
900500000 900999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 901000000 K is 1000000000
901000000 901499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 901500000 K is 1000000000
901500000 901999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 902000000 K is 1000000000
902000000 902499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 902500000 K is 1000000000
902500000 902999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 903000000 K is 1000000000
903000000 903499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 903500000 K is 1000000000
903500000 903999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 904000000 K is 1000000000
904000000 904499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 904500000 K is 1000000000
904500000 904999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 905000000 K is 1000000000
905000000 905499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 905500000 K is 1000000000
905500000 905999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 906000000 K is 1000000000
906000000 906499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 906500000 K is 1000000000
906500000 906999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 907000000 K is 1000000000
907000000 907499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 907500000 K is 1000000000
907500000 907999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 908000000 K is 1000000000
908000000 908499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 908500000 K is 1000000000
908500000 908999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 909000000 K is 1000000000
909000000 909499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 909500000 K is 1000000000
909500000 909999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 910000000 K is 1000000000
910000000 910499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 910500000 K is 1000000000
910500000 910999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 911000000 K is 1000000000
911000000 911499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 911500000 K is 1000000000
911500000 911999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 912000000 K is 1000000000
912000000 912499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 912500000 K is 1000000000
912500000 912999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 913000000 K is 1000000000
913000000 913499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 913500000 K is 1000000000
913500000 913999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 914000000 K is 1000000000
914000000 914499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 914500000 K is 1000000000
914500000 914999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 915000000 K is 1000000000
915000000 915499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 915500000 K is 1000000000
915500000 915999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 916000000 K is 1000000000
916000000 916499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 916500000 K is 1000000000
916500000 916999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 917000000 K is 1000000000
917000000 917499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 917500000 K is 1000000000
917500000 917999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 918000000 K is 1000000000
918000000 918499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 918500000 K is 1000000000
918500000 918999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 919000000 K is 1000000000
919000000 919499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 919500000 K is 1000000000
919500000 919999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 920000000 K is 1000000000
920000000 920499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 920500000 K is 1000000000
920500000 920999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 921000000 K is 1000000000
921000000 921499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 921500000 K is 1000000000
921500000 921999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 922000000 K is 1000000000
922000000 922499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 922500000 K is 1000000000
922500000 922999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 923000000 K is 1000000000
923000000 923499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 923500000 K is 1000000000
923500000 923999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 924000000 K is 1000000000
924000000 924499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 924500000 K is 1000000000
924500000 924999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 925000000 K is 1000000000
925000000 925499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 925500000 K is 1000000000
925500000 925999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 926000000 K is 1000000000
926000000 926499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 926500000 K is 1000000000
926500000 926999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 927000000 K is 1000000000
927000000 927499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 927500000 K is 1000000000
927500000 927999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 928000000 K is 1000000000
928000000 928499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 928500000 K is 1000000000
928500000 928999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 929000000 K is 1000000000
929000000 929499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 929500000 K is 1000000000
929500000 929999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 930000000 K is 1000000000
930000000 930499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 930500000 K is 1000000000
930500000 930999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 931000000 K is 1000000000
931000000 931499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 931500000 K is 1000000000
931500000 931999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 932000000 K is 1000000000
932000000 932499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 932500000 K is 1000000000
932500000 932999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 933000000 K is 1000000000
933000000 933499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 933500000 K is 1000000000
933500000 933999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 934000000 K is 1000000000
934000000 934499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 934500000 K is 1000000000
934500000 934999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 935000000 K is 1000000000
935000000 935499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 935500000 K is 1000000000
935500000 935999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 936000000 K is 1000000000
936000000 936499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 936500000 K is 1000000000
936500000 936999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 937000000 K is 1000000000
937000000 937499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 937500000 K is 1000000000
937500000 937999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 938000000 K is 1000000000
938000000 938499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 938500000 K is 1000000000
938500000 938999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 939000000 K is 1000000000
939000000 939499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 939500000 K is 1000000000
939500000 939999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 940000000 K is 1000000000
940000000 940499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 940500000 K is 1000000000
940500000 940999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 941000000 K is 1000000000
941000000 941499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 941500000 K is 1000000000
941500000 941999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 942000000 K is 1000000000
942000000 942499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 942500000 K is 1000000000
942500000 942999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 943000000 K is 1000000000
943000000 943499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 943500000 K is 1000000000
943500000 943999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 944000000 K is 1000000000
944000000 944499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 944500000 K is 1000000000
944500000 944999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 945000000 K is 1000000000
945000000 945499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 945500000 K is 1000000000
945500000 945999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 946000000 K is 1000000000
946000000 946499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 946500000 K is 1000000000
946500000 946999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 947000000 K is 1000000000
947000000 947499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 947500000 K is 1000000000
947500000 947999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 948000000 K is 1000000000
948000000 948499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 948500000 K is 1000000000
948500000 948999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 949000000 K is 1000000000
949000000 949499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 949500000 K is 1000000000
949500000 949999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 950000000 K is 1000000000
950000000 950499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 950500000 K is 1000000000
950500000 950999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 951000000 K is 1000000000
951000000 951499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 951500000 K is 1000000000
951500000 951999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 952000000 K is 1000000000
952000000 952499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 952500000 K is 1000000000
952500000 952999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 953000000 K is 1000000000
953000000 953499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 953500000 K is 1000000000
953500000 953999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 954000000 K is 1000000000
954000000 954499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 954500000 K is 1000000000
954500000 954999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 955000000 K is 1000000000
955000000 955499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 955500000 K is 1000000000
955500000 955999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 956000000 K is 1000000000
956000000 956499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 956500000 K is 1000000000
956500000 956999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 957000000 K is 1000000000
957000000 957499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 957500000 K is 1000000000
957500000 957999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 958000000 K is 1000000000
958000000 958499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 958500000 K is 1000000000
958500000 958999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 959000000 K is 1000000000
959000000 959499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 959500000 K is 1000000000
959500000 959999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 960000000 K is 1000000000
960000000 960499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 960500000 K is 1000000000
960500000 960999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 961000000 K is 1000000000
961000000 961499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 961500000 K is 1000000000
961500000 961999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 962000000 K is 1000000000
962000000 962499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 962500000 K is 1000000000
962500000 962999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 963000000 K is 1000000000
963000000 963499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 963500000 K is 1000000000
963500000 963999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 964000000 K is 1000000000
964000000 964499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 964500000 K is 1000000000
964500000 964999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 965000000 K is 1000000000
965000000 965499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 965500000 K is 1000000000
965500000 965999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 966000000 K is 1000000000
966000000 966499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 966500000 K is 1000000000
966500000 966999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 967000000 K is 1000000000
967000000 967499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 967500000 K is 1000000000
967500000 967999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 968000000 K is 1000000000
968000000 968499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 968500000 K is 1000000000
968500000 968999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 969000000 K is 1000000000
969000000 969499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 969500000 K is 1000000000
969500000 969999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 970000000 K is 1000000000
970000000 970499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 970500000 K is 1000000000
970500000 970999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 971000000 K is 1000000000
971000000 971499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 971500000 K is 1000000000
971500000 971999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 972000000 K is 1000000000
972000000 972499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 972500000 K is 1000000000
972500000 972999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 973000000 K is 1000000000
973000000 973499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 973500000 K is 1000000000
973500000 973999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 974000000 K is 1000000000
974000000 974499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 974500000 K is 1000000000
974500000 974999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 975000000 K is 1000000000
975000000 975499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 975500000 K is 1000000000
975500000 975999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 976000000 K is 1000000000
976000000 976499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 976500000 K is 1000000000
976500000 976999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 977000000 K is 1000000000
977000000 977499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 977500000 K is 1000000000
977500000 977999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 978000000 K is 1000000000
978000000 978499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 978500000 K is 1000000000
978500000 978999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 979000000 K is 1000000000
979000000 979499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 979500000 K is 1000000000
979500000 979999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 980000000 K is 1000000000
980000000 980499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 980500000 K is 1000000000
980500000 980999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 981000000 K is 1000000000
981000000 981499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 981500000 K is 1000000000
981500000 981999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 982000000 K is 1000000000
982000000 982499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 982500000 K is 1000000000
982500000 982999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 983000000 K is 1000000000
983000000 983499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 983500000 K is 1000000000
983500000 983999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 984000000 K is 1000000000
984000000 984499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 984500000 K is 1000000000
984500000 984999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 985000000 K is 1000000000
985000000 985499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 985500000 K is 1000000000
985500000 985999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 986000000 K is 1000000000
986000000 986499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 986500000 K is 1000000000
986500000 986999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 987000000 K is 1000000000
987000000 987499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 987500000 K is 1000000000
987500000 987999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 988000000 K is 1000000000
988000000 988499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 988500000 K is 1000000000
988500000 988999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 989000000 K is 1000000000
989000000 989499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 989500000 K is 1000000000
989500000 989999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 990000000 K is 1000000000
990000000 990499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 990500000 K is 1000000000
990500000 990999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 991000000 K is 1000000000
991000000 991499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 991500000 K is 1000000000
991500000 991999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 992000000 K is 1000000000
992000000 992499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 992500000 K is 1000000000
992500000 992999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 993000000 K is 1000000000
993000000 993499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 993500000 K is 1000000000
993500000 993999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 994000000 K is 1000000000
994000000 994499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 994500000 K is 1000000000
994500000 994999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 995000000 K is 1000000000
995000000 995499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 995500000 K is 1000000000
995500000 995999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 996000000 K is 1000000000
996000000 996499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 996500000 K is 1000000000
996500000 996999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 997000000 K is 1000000000
997000000 997499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 997500000 K is 1000000000
997500000 997999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 998000000 K is 1000000000
998000000 998499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 998500000 K is 1000000000
998500000 998999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 999000000 K is 1000000000
999000000 999499999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1
I is 999500000 K is 1000000000
999500000 999999999
INFO:root:Using green thread (gevent)-enabled ZINC API (Forced: True)
INFO:root:Creating production ZINC application
INFO:root:ZINC production application loaded
INFO:root:SELECT chembl21a.sea.sea_id AS chembl21a_sea_sea_id, chembl21a.sea.sub_id_fk AS chembl21a_sea_sub_id_fk, chembl21a.sea.gene_fk AS chembl21a_sea_gene_fk, chembl21a.sea.predtype AS chembl21a_sea_predtype, chembl21a.sea.predvalue AS chembl21a_sea_predvalue, chembl21a.sea.pvalue AS chembl21a_sea_pvalue, chembl21a.sea.maxtc AS chembl21a_sea_maxtc 
FROM chembl21a.sea JOIN substance ON substance.sub_id = chembl21a.sea.sub_id_fk 
WHERE substance.sub_id BETWEEN :sub_id_1 AND :sub_id_2 AND substance.purchasable > :purchasable_1 AND (EXISTS (SELECT 1 
FROM chembl21a.sea 
WHERE substance.sub_id = chembl21a.sea.sub_id_fk))
 LIMIT :param_1