This are the latest commercially available building blocks. 

purchasability levels:
50 - in stock top tier
40 - in stock
30 - via agent
20 - on demand
10 - boutique

Please see the narrative below for what this means.

	Name	Last modified	Size	Description
	Parent Directory		-
	bb.50.txt.gz	2022-03-17 14:08	30M
	bb_50.smi.gz	2022-03-17 14:08	13M
	bb.40.txt.gz	2022-03-17 14:09	13M
	bb_40.smi.gz	2022-03-17 14:09	5.6M
	bb.30.txt.gz	2022-03-17 14:09	90K
	bb_30.smi.gz	2022-03-17 14:09	43K
	bb.20.txt.gz	2022-03-17 14:10	241M
	bb_20.smi.gz	2022-03-17 14:10	100M
	bb.10.txt.gz	2022-03-17 14:11	1.6G
	bb_10.smi.gz	2022-03-17 14:12	652M
	bb_forsale.smi.gz	2022-03-17 14:12	771M
	bb_instock.smi.gz	2022-03-17 14:12	18M

More info about purchasability of building blocks

50 - we expect that >90% of these compounds are available.
arrival in 1 week
Typically cost around $1/mg, possibly less,  thus $250 for 250 mg, something like that. 

40 - we expect that  >80% of these compounds are avaialble. 
arrival ?? maybe 2 weeks ??
Cost not so well known, likely more. 

30 - like 40, but via a procurement agent likely to be slower, more expensive.

20 - typically either 6 weeks and 80% success OR quicker but more expensive. 

10 - typically expensive, but for sale!  Some of these might be $2000 for 100mg or more.
But someone will make them for you, so you don't have to. 70% success rate perhaps. 
median price might be $600 for 100 mg.